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Hello, I blog!

I write with no particular theme in mind, because I am random like that.

03 2011

7:40 PM



Cyclosphorine, please be nice to me. Kthx.

For the past one and a half weeks, I’ve been on Cyclosphorine to suppress my immune system. (I suffer from autoimmune urticaria since about 6 years ago, which turned aggressive only recently, basically causing my body’s immune system to attack my own skin and occasionally, joints.)

Cyclosporine belongs to the group of medicines known as immunosuppressive agents. It is used to reduce the body’s natural immunity in patients who receive organ (for example, kidney, liver, and heart) transplants.

When a patient receives an organ transplant, the body’s white blood cells will try to get rid of (reject) the transplanted organ. Cyclosporine works by preventing the white blood cells from doing this.

(Adapted from MayoClinic.)

It’s a pretty darn strong medication, commonly used to suppress the immune system of transplant patients to prevent organ rejection. I initially had my reservations about it, because of its multitude of side-effects, but eventually took the plunge because otherwise, the illness would just get worse. (And I’ve stopped responding to even the strongest H1 and H2-blockers out there.)

Well, it’s taking its toll – numb fingers and toes, the constant feeling of fatigue and weakness and the occasional nausea. And recently, low-grade fever. All part and parcel of being on Cyclosphorine but side-effects aside, it’s doing a pretty good job and preventing my flare-ups … so far.

I also need regular blood tests to ensure my white cells don’t fall too low, or that my kidneys don’t fail.

Above all, I’m also glad I’ve (finally) managed to find an awesome allergist/rheumatologist to take care of me. He’s one of the very few here in Singapore, so I’m mightily glad.

The doctor, a couple of friends and this forum (contributed to by a host of other people around the world with the same medical condition) has been a great source of support so far.

So, if you know me in real life and have been wondering why hadn’t I called you out in aeons for shopping/lunch/dinner/just bumming around, now you know why. I’ve been basically devoid of energy for quite a while. Please be patient with me, though – I’ll be back to my old self once I assimilate to Cyclosphorine!

Until then, please pardon me while I conk back off to sleep in bed. G’nitey.

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  • 08 May 2011
    11:20 PM

    Dr. J

    Hi Brenda!

    I stumbled onto your site when I Googled Brendology to see if it existed after I “made” up the term yesterday :-) Well, obviously it does! I am a surgeon in Florida, USA ( I write a health and fitness column on the Internet). I’m sorry about the medical challenges you have to face, yet your spunky attitude is very impressive. Perhaps that we share the Scorpio (Western astrology) birth sign has some relevance. At any rate, just a hello from the other side of our spaceship earth. I wish you well!

    • 09 May 2011
      12:10 AM


      Hello Dr. J! Thanks for dropping by my blog and for saying hi. Scorpio folks are indeed funky people. (; Will definitely check out your column. You have a great weekend!

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